Female Urogenital Tract Mycoplasma Infection and Drug - Resistance Evolution

[Objective]To study female urogenital tract mycoplasma infection and drug- resistance evolution. [Methods]Mycoplasma culture and drug sensitivity tests were conducted on the urogenital tract mycoplasma infected patients during the period of 2002 to 2004; analysis was made on the changes of drug sensitivity. [Results] Among the 117 mycoplasma positive cases in 2002, 82.9% were infected with Ure aplesma urealyticum (Uu), 2.6% with Mycoplasma hominis (Mh), 14.5% with both Uu and Mh; among the 126 mycoplasma positive cases in 2004, Uu infection counted to 83.3% , Mh infection 4.0% , and double infection 12.7% . Compared with 2002, the drug resistance rates to minomycin, doxycycline and josamycin increased obviously in 2004; but the drug resistance rates to roxithromycin, azithromycin, chindamycin, ofioxacin, spartioxacin and levofloxacin showed no significant changes. [ Conclusion] Mycoplasma has a high rate of drug - resistance, and the drug sensitivity evolves with the time. Treatment for mycoplasma should be based on the results of drug sensitivity tests. Josamycin can be used as the first choice.