CT and MR diagnosis of periventricular leukomalacia in children

Objective To study the etiology and clinics as well as CT/MR diagnostic value of periventricular leukomalacia(PVL)in children.Methods Totally 46 cases of periventricular leukomalacia proved by CT,MR and clinic were retrospectively analyzed.Results Totally 28 cases were premature newborn babies(61%)and 18 cases were fullmature newborn(39%)with hypoxic ischemic encephalopathy.In 46 cases with PVL,the mild,moderate,and severe cases was 19,15 and 12respectively(included 4 cases with hypoplasia of corpus callosum).CT and MR showed that the lateral ventricle enlarged in different degrees and the periventricle white matter decreased,and the white matter lesions at periventricular appeared as long T1and T2signal intenity.Conclusions PVL is a main factor of cerebral palsy.CT and MR have important value in diagnosis of PVL.