Extraction Process by Orthogonal Design Chankangle Particles in Water

Objective:To optimize the extracting technology of baicalin preferably Chankangle granule( 产康乐颗粒). Methods:The water content of extract to yield and baicalin extract stem Chankangle particles in the evaluation, selection, solvent ratio, soaking time, extracting time were the main factors and the three levels; The yield of dry extract and the main active ingredient transfer rate that can reflect the extraction efficiency was selected. Results:The best the extraction conditions for the first time with 10 times amount of water, decocting 1.5 h; The second time with 8 times amount of water, decocting 1h. Conclusion:The method is simple, accurate, and reproducible, for the extraction of baicalin from Chankangle in the particles provide the basis for the determination.