Analysis of pathogenic bacteria and their drug resistance in patients with lower respiratory infection in the department of respiratory medicine in 2011

Objective To investigate the pathogenic bacteria distribution and their drug resistance in patients with lower respiratory infection.Methods The sputum of all patients was collected and cultured,and then the sputum samples were analyzed.Results The results showed that gram-negative bacteria took up 71.8%,fungi 24.4% and gram-positive bacteria 3.8%.The main kind of gram-negative bacteria was pseudomonas aemginosa(29.3%),followed by baumanii(13.5%) and klebsiella pneumoniae(10.5%).Fungi mainly were candida albicans and gram-positive bacteria were staphylococcus aureus.Gram-negative bacteria showed the lowest resistance to imipenem,followed by amikacin.Staphylococcus aureus had no resistance to vancomycin and linezolid,but showed a certain resistance to meticillin sodium.Conclusion Most bacteria in patients with lower respiratory infection show a certain resistance to many antibiotics.Therefore,the rational use of antibiotics is very important for the containment of bacterial resistance.