The relationship between oral squamous cell carcinoma of MMP-1, MMP-2, UPA's expression of tumor invasion and metastasis

Objective To investigate the relationship between MMP-1,MMP-2,UPA's expression in oral squamous cell carcinoma invasion and metastasis,to provide experimental evidence for tumor treatment and prognosis.Methods 60 patients with oral squamous cell carcinoma patients in our hospitalwere for the study,immunohistochemical detection of adjacent normal tissue and cancer tissue in MMP-1,the MM P-2,UPA's content.Results Patients with oral squamous cell carcinoma tumor cavity adjacent normal tissue MMP-1,MMP-2,the UPA's content difference were significant(P 0.05).Conclusion Oral squamous cell carcinoma of MMP-1,MMP-2,UPA's expression in tumor invasion and metastasis are closely related,it is possible to become the evaluation of invasion,metastasis indicators.