Rabeprazole combined with Mosapride on reflux esophagitis: clinical observation of 60 cases

Objective To investigate the effect of rabeprazoloe combined with mosapride on reflux esophagitis.Methods 120 patients with reflux esophagitis were randomly divided into two groups.In treatment group,60 patients were given rabeprazole 20 mg,one time a day taken by mouth and mosapride 5 mg,three times a day taken by mouth,while in control group,60 patients were given famotidine 20 mg,two times a day taken orally and mosapride 5mg,three times a day taken orally.The treatment course of two groups was all 8 weeks.Gastroscope was performed in 8 weeks to observe the effective rate.Results The clinical effective rate in treatment group was 96.6%,while 78.3% respectively in control group.The differencebetween the two groups was statistically significant(P 0.01).Conclusion Rabeprazole combined with mosapride showes a better clinical efficacy than famotidine combined with mosapride in treatment of reflux esophagitis.