Preparation and Quality Criteria of Yigankang Oral Liquid
Cui Shu-yun
Abstract
Cui Shu-yun
Abstract
OBJECTIVE:To prepare Yigankang oral liquid and establish its quality criteria.METHODS: The constituents such as Radix Astragali, Radix Codonopsis and Radix Salvia Miltiorrhiza in Yigankang oral liquid were identified by TLC. The content of Lobetyolin in Yigankang oral liquid was determined by HPLC. RESULTS: The characteristic TLC spots were noted. Lobetyolin showed a good linear relationship in the a range of 0.036~1.317 mg·mL-1(r=0.999 9) and the average recovery was 100.10% with RSD at 1.70%. CONCLUSION: The method is simple and reliable, and it can be used for the quality control of Yigankang oral liquid.
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OBJECTIVE:To prepare Yigankang oral liquid and establish its quality criteria.METHODS: The constituents such as Radix Astragali, Radix Codonopsis and Radix Salvia Miltiorrhiza in Yigankang oral liquid were identified by TLC. The content of Lobetyolin in Yigankang oral liquid was determined by HPLC. RESULTS: The characteristic TLC spots were noted. Lobetyolin showed a good linear relationship in the a range of 0.036~1.317 mg·mL-1(r=0.999 9) and the average recovery was 100.10% with RSD at 1.70%. CONCLUSION: The method is simple and reliable, and it can be used for the quality control of Yigankang oral liquid.
Key concepts: Radix (gastropod), Codonopsis, Salvia miltiorrhiza, Chromatography, High-performance liquid chromatography, Linear relationship, Chemistry, Traditional medicine