Efficacy observation of pulmonary invasive fungal infection treated with itraconazole

Objective:To compare clinical efficacy of micafungin and itraconazole treatment of pulmonary invasive fungal infections(IPFI).Methods:80 patients in our hospital from January 2007 to February 2010 were divided into micafungin group and itraconazole group according to the different treatment methods,micafungin group 38 cases,itraconazole group 42 cases,15 days for a course of treatment,after two courses compared the clinical efficacy and the incidence of adverse reactions,and make statistical analysis.Results:Itraconazole group markedly effective rate and total effective rate was significantly higher than the micafungin group,two groups were significant different(P0.05),difference of adverse reactions the was not significant between two groups(P0.05).Conclusion:Itraconazole treatment of pulmonary invasive fungal infections is effective,side-effect is small,it should be promoted.