ScholarLens Back to search
2008•Clinical MedicineRequires access

Effect of recombinant human growth hormone in patients of COPD with BiPAP ventilation

Yefen Chen

Open publisher page 0 citations

Abstract

Objective To investigate the effects of recombinant human growth hormone(rHGH) in patients of chronic obstructive pulmonary disease(COPD) with non-invasion bi-level positive airway pressure(BiPAP) ventilation.Methods Thirty patients with COPD of respiratory failure with BiPAP ventilation were randomly assigned to rHGH group and control group.Patients in rHGH group were given rHGH 8 IU/d.The treatment days,the indexes of nutritional status,immunological function and blood glucose were recorded and compared between the two groups.Results The average treatment days in rHGH group was less than those in control group,P0.05.After 7 treatment days,the activity of CD4,NKC and the levels of albumin,transferrin and prealbumin levels were increased in rHGH group,P0.05.Conclusion The treatment days in rHGH group could be reduced,rHGH can improve the nutritional status and immunological function in patients with BiPAP ventilation.

About this research paper

What this paper is about

Objective To investigate the effects of recombinant human growth hormone(rHGH) in patients of chronic obstructive pulmonary disease(COPD) with non-invasion bi-level positive airway pressure(BiPAP) ventilation.Methods Thirty patients with COPD of respiratory failure with BiPAP ventilation were randomly assigned to rHGH group and control group.Patients in rHGH group were given rHGH 8 IU/d.The treatment days,the indexes of nutritional status,immunological function and blood glucose were recorded and compared between the two groups.Results The average treatment days in rHGH group was less than those in control group,P0.05.After 7 treatment days,the activity of CD4,NKC and the levels of albumin,transferrin and prealbumin levels were increased in rHGH group,P0.05.Conclusion The treatment days in rHGH group could be reduced,rHGH can improve the nutritional status and immunological function in patients with BiPAP ventilation.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the effects of recombinant human growth hormone(rHGH) in patients of chronic obstructive pulmonary disease(COPD) with non-invasion bi-level positive airway pressure(BiPAP) ventilation.Methods Thirty patients with COPD of respiratory failure with BiPAP ventilation were randomly assigned to rHGH group and control group.Patients in rHGH group were given rHGH 8 IU/d.The treatment days,the indexes of nutritional status,immunological function and blood glucose were recorded and compared between the two groups.Results The average treatment days in rHGH group was less than those in control group,P0.05.After 7 treatment days,the activity of CD4,NKC and the levels of albumin,transferrin and prealbumin levels were increased in rHGH group,P0.05.Conclusion The treatment days in rHGH group could be reduced,rHGH can improve the nutritional status and immunological function in patients with BiPAP ventilation.

Key concepts: Medicine, Human growth hormone, COPD, Ventilation (architecture), Internal medicine, Pulmonary function testing, Positive airway pressure, Respiratory system

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effect of recombinant human growth hormone in patients of COPD with BiPAP ventilation — Research Paper | ScholarLens