Relationship Between Serum Tumor Markers Detection and Early Diagnosis of Lung Cancer

Objective Investigate the relationship between serum tumor markers detection and early diagnosis of lung cancer. Methods 91 cases of lung cancer patients were as lung cancer group, the serum of two groups were detected selected in our hospital from February 2013 to February 2014 in respiratory department of our hospital in tumor marker,and selected 50 cases of healthy as healthy group. compared two groups of patients with tumor marker levels, serum carcinoma embryonic antigen(CEA), carbohydrate antigen 125(CA125), carbohydrate antigen 153(CA153) and neuron specific enolase(NSE) levels. Results Lung cancer group of CEA, CA125, CA153 and neuron specific enolase(NSE) four level were significantly higher than those of the healthy group, the difference has statistical significance(P0.05); four tumor markers joint monitoring and separate the tumor markers matter index can significantly improve the sensitivity of diagnosis of lung cancer, the difference was not statistically significant(P0.05); recurrence in patients with CEA, CA125, CA153 and neuron specific enolase(NSE) four level were significantly higher than those of the not relapsed patients, the difference was not statistically significant(P0.05). Conclusion S erum tumor markers detection has important clinical value in early diagnosis of lung cancer. The combined detection of tumor markers can improve the sensitivity of diagnosis of lung cancer.