Evaluate on effect of measles vaccine supplementary immunization activities among 8 months to 14 years children

Objective To analyze the effect and influencing factors of Measles Vaccine(MV) Supplementary Immunization Activities(SIA) among 8 months to 14 years children in Hefei,monitor status of population immunization and epidemic disease.Methods Measles Vaccine SIA was implemented among 8 months to 14 years children all over the city in October 2009.A stratified random sampling method was adopted to focus study on community vaccination clinics,kindergartens,elementary schools and middle schools,analyze the antibody level of the target population before and after SIA.Study epidemic status of measles cases before and after SIA with statistical description method.Results The total rate of MV vaccination was 98.04%.Measles antibody positive rate and the GMT level rose after SIA and measles antibody positive rate was 91.38%.The GMT level of 1-4 years children and≥3 MV doses individuals were the highest,respectively,logistic multiple regression analysis revealed significant difference between the GMT level of ≥3 MV doses and one MV dose individuals.The measles incidence was 8.1 per million in 2010,decreased 91.86% compared with that of 2009.The largest number of cases occurred among 1 years children,the proportion of cases with ≥2 MV doses were the lowest.Conclusion In the epidemic stage of measles gradually reduction,important aspects of measures are the regulation of routine vaccination of 1 dose and 2 doses MV targeting children timely,the conducting of MV supplementary immunization activities at suitable time.Strengthening the quality management of immune programming and cases monitoring are also the critical factors.