2012•Journal of Clinical Medicine in PracticeRequires access

Serum C-reactive protein,serum ferritin and its relationship with the severity of diabetic retinopathy

Heng Miao

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Abstract

Objective To investigate serum C-reactive protein,serum ferritin and its relationship with the severity of diabetic retinopathy.Methods According to the fundus examination,hospitalized patients with type 2 diabetes were randomly chosen and divided into three groups,including no diabetic retinopathy group(NDR group,n=21),non-proliferative diabetic retinopathy group(NPDR group,n=20) and proliferative diabetic ertinopathy group(PDR group,n=19).The differences in the level of C-reactive protein and serum ferritin were analyzed.Results Total C-reactive protein,serum ferritin in NDR group,NPDR group and PDR group gradually increased,and the differences among three groups were statistically significant(P0.05).Logistic multivariate regression analysis showed that C-reactive protein and serum ferritin were independent risk factors of diabetic retinopathy.Conclusion The levels of C-reactive protein and serum ferritin which have some certain relationship with the severity of diabetic retinopathy should be monitored as early as possible.

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Objective To investigate serum C-reactive protein,serum ferritin and its relationship with the severity of diabetic retinopathy.Methods According to the fundus examination,hospitalized patients with type 2 diabetes were randomly chosen and divided into three groups,including no diabetic retinopathy group(NDR group,n=21),non-proliferative diabetic retinopathy group(NPDR group,n=20) and proliferative diabetic ertinopathy group(PDR group,n=19).The differences in the level of C-reactive protein and serum ferritin were analyzed.Results Total C-reactive protein,serum ferritin in NDR group,NPDR group and PDR group gradually increased,and the differences among three groups were statistically significant(P0.05).Logistic multivariate regression analysis showed that C-reactive protein and serum ferritin were independent risk factors of diabetic retinopathy.Conclusion The levels of C-reactive protein and serum ferritin which have some certain relationship with the severity of diabetic retinopathy should be monitored as early as possible.

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Available abstract

Objective To investigate serum C-reactive protein,serum ferritin and its relationship with the severity of diabetic retinopathy.Methods According to the fundus examination,hospitalized patients with type 2 diabetes were randomly chosen and divided into three groups,including no diabetic retinopathy group(NDR group,n=21),non-proliferative diabetic retinopathy group(NPDR group,n=20) and proliferative diabetic ertinopathy group(PDR group,n=19).The differences in the level of C-reactive protein and serum ferritin were analyzed.Results Total C-reactive protein,serum ferritin in NDR group,NPDR group and PDR group gradually increased,and the differences among three groups were statistically significant(P0.05).Logistic multivariate regression analysis showed that C-reactive protein and serum ferritin were independent risk factors of diabetic retinopathy.Conclusion The levels of C-reactive protein and serum ferritin which have some certain relationship with the severity of diabetic retinopathy should be monitored as early as possible.

Key concepts: Medicine, Ferritin, Diabetic retinopathy, C-reactive protein, Internal medicine, Logistic regression, Fundus (uterus), Diabetes mellitus

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