2004•Unpublished venueRequires access

MRI Manifestations of Focal Nodular Hyperplasia of the Liver

Zhou Kangrong

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Abstract

Objective To analyze MRI features of focal nodular hyperplasia (FNH) of the liver, and to make a further understanding of FNH. Materials and Methods Dynamic contrast-enhanced FMPSPGR was performed in 18 patients with pathologically proved FNH (total 24 lesions). SE T 1WI, PDWI and T 2WI were completed in 11 cases, and SE T 1WI and FSE T 2WI in 7 cases.Results Of 24 lesions, central scar, the typical sign of FNH, was found in 2, while atypical central scar was seen in 9. Marked enhancement during arterial phase was demonstrated in 23, and during portal phase in 7 lesions. Moderate enhancement was seen in 15 lesions. During balanced phase, 16 lesions showed moderate enhancement and 8 lesions had mild enhancement. During delayed phase, 12 of 17 lesions showed mild enhancement and the other 5 lesions showed iso-signal, central linear or spotted enhancement was seen in 4 lesions.Conclusion Correct diagnosis of FNH , up to 83.3%, can be made by MRI. For atypical FNH, SPIO or Gd-EOB-DTPA enhanced dynamic scanning should be used and clinical material should be taken into account.

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Objective To analyze MRI features of focal nodular hyperplasia (FNH) of the liver, and to make a further understanding of FNH. Materials and Methods Dynamic contrast-enhanced FMPSPGR was performed in 18 patients with pathologically proved FNH (total 24 lesions). SE T 1WI, PDWI and T 2WI were completed in 11 cases, and SE T 1WI and FSE T 2WI in 7 cases.Results Of 24 lesions, central scar, the typical sign of FNH, was found in 2, while atypical central scar was seen in 9. Marked enhancement during arterial phase was demonstrated in 23, and during portal phase in 7 lesions. Moderate enhancement was seen in 15 lesions. During balanced phase, 16 lesions showed moderate enhancement and 8 lesions had mild enhancement. During delayed phase, 12 of 17 lesions showed mild enhancement and the other 5 lesions showed iso-signal, central linear or spotted enhancement was seen in 4 lesions.Conclusion Correct diagnosis of FNH , up to 83.3%, can be made by MRI. For atypical FNH, SPIO or Gd-EOB-DTPA enhanced dynamic scanning should be used and clinical material should be taken into account.

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Available abstract

Objective To analyze MRI features of focal nodular hyperplasia (FNH) of the liver, and to make a further understanding of FNH. Materials and Methods Dynamic contrast-enhanced FMPSPGR was performed in 18 patients with pathologically proved FNH (total 24 lesions). SE T 1WI, PDWI and T 2WI were completed in 11 cases, and SE T 1WI and FSE T 2WI in 7 cases.Results Of 24 lesions, central scar, the typical sign of FNH, was found in 2, while atypical central scar was seen in 9. Marked enhancement during arterial phase was demonstrated in 23, and during portal phase in 7 lesions. Moderate enhancement was seen in 15 lesions. During balanced phase, 16 lesions showed moderate enhancement and 8 lesions had mild enhancement. During delayed phase, 12 of 17 lesions showed mild enhancement and the other 5 lesions showed iso-signal, central linear or spotted enhancement was seen in 4 lesions.Conclusion Correct diagnosis of FNH , up to 83.3%, can be made by MRI. For atypical FNH, SPIO or Gd-EOB-DTPA enhanced dynamic scanning should be used and clinical material should be taken into account.

Key concepts: Focal nodular hyperplasia, Medicine, Contrast enhancement, Radiology, Magnetic resonance imaging, Nuclear medicine, Pathology, Hepatocellular carcinoma

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