Clinical research of hemodynamics monitoring in lung transplantation

Objective To evaluate the hemodynamics during lung transplantation via PICCO and Swan-Ganz monitoring.Methods Twenty-three ASA Ⅲ or Ⅳ patients,aged 17 to 72 years,undergoing lung transplantation surgery were involved in this study. All patients received central venous,Swan-Ganz,and PiCCO catheter placement. The hemodynamic parameters such as PAP,PCCO,CO,GEDI,ITBI,CVP,PAOP,SVI,ELWI and PVPI were recorded after induction(T0),30 min after one-lung ventilation(T1),10 min after pulmonary artery clamping(T2),30 min after pulmonary artery unclamping(T3),on the end of surgery(T4). Results PAP and PPV increased but PCCO and CO decreased at T1 and T2when compared with T0 (P0.05). PCCO and CO increased at T3 and T4 compared with T1 and T2(P0.05).GEDI,ITBI,ELWI and PVPI increased at T3 and T4 than T0 (P0.05). GEDI was correlated to SVI (r=0.66,P0.01),TTBI was correlated to SVI(r=0.65,P0.01). PAOP was correlated to SVI(r=0.18). ELWI was correlated to PVPI(r=0.85,P0.01).Conclusion The hemodynamics is unstable during lung transplantation. PICCO together with Swan-Ganz is a good choice to monitor the cardiac and pulmonary function during lung transplantation.