Comparison of clinical effect between enteral nutrition and parenteral nutrition on patients with severe acute pancreatitis

Objective To compare the clinical effect of enteral nutrition(EN) and parenteral nutrition(PN) in the treatment of severe acute pancreatitis(SAP).Methods There were 48 inpatients of SAP from June 1st,2008 to June 1st,2011,which were divided into EN group(24 cases) and PN group(24 cases) randomly by the order of visiting doctors.Analysis was conducted on the general situations,the efficacy of two weeks' treatment,including the improvement of nutrition,complications of the treatment,mortality rate and cure rate.Results After the nutritional support,contrast to PN group,EN group achieved better results,such as enhancement of serum albumin(35.92±5.31) g/L vs(29.02±4.68) g/L(P0.01),reduction of white blood cell count(8.27±2.64)×109/L vs(10.89±3.16)×109/L(P0.05),less occurrence of complications such as ARDS and infection(16.7% vs 37.5%,P0.01).Conclusion As the major treatment of SAP,early EN support is more safe and effective to patients in condition without contraindications than PN support,and EN support shows advantages on melioration of nutrition and reduction of complications.