Mucoepidermoid carcinoma of esophagus:a clinicopathological analysis

Objective The clinical features,pathological characteristics and biological behaviors of mucoepidermoid carcinoma of esophagus were studied.Methods Two cases of mucoepidermoid carcinoma of esophagus were reported and analyzed in terms of clinicopathologic changes,immunohisochemical findings and review of literature review.Results Histologically,the tumors were composed of a intimate mixture of squamous cells,mucus secreting carcinoma cells and cells of an intermediate type.Proliferating cell nuclear antigen(PCNA),carcinoembryonic antigen(CEA) and so on were stained in the resected specimens by immunohistochemistry.Conclusion The histologial features of this tumor seemed to originate from esophageal glands and their ducts,and the tumor is aggressive and has a poor prognosis.