2000•Chinese Journal of DermatologyRequires access

The Serum Level of Interleukin-18 and Its Correlation with Interferon gamma in Patients with Condyloma Acuminatum

Qian Qi-fen, Std Control

Abstract

Objective To study the role of interleukin－ 18(IL－ 18) and interferon gamma(IFN－γ ) in the pathogenesis of condyloma acuminatum(CA), and the relationship between the two cytokines. Methods The serum levels of IL－ 18 and IFN－γ were determined by double antibody sandwich enzyme linked immunosorbent assay in 36 patients with CA and in 30 normal controls.Results The serum levels of IL－ 18 and IFN－γ were significantly lower in CA patients than those in normal controls(P

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Key concepts: Condyloma Acuminatum, Pathogenesis, Interferon gamma, Positive correlation, Immunology, Interleukin, Interferon, Interferon γ