ScholarLens Back to search
2002•Journal of Dermatology and VenereologyRequires access

Study on the level of IFN-γ,IL-2 in serum of patients with different course of condyloma acuminata

Yating Tu

Open publisher page 0 citations

Abstract

Objective:To investigate the role of the changes of the expression of the level of IFN-γ,IL-2 in serum of patients with different course of condyloma acuminata(CA)in the immune pathogenesis of CA.Methods:solid sandwich Enzyme-Linked Immunoadsorbent assay(ELISA)were performed for detecting the level of IFN-γ,IL-2 in serum of 60 cases with different course of CA.Results:The level of IFN-γ,IL-2 in serum of the group of CA is significantly lower than that of the group of normal control(P0.01),and the level of IFN-γ,IL-2 in serum of the group of long course of CA is significantly lower than that of the group of short course(P0.01).Conclusion:Patients with CA were characterized by the suppressed secretion of the TH1-associated cytokines(eg:IFN-γ,IL-2),this might play an important role in the immune pathogenesis of CA.

About this research paper

What this paper is about

Objective:To investigate the role of the changes of the expression of the level of IFN-γ,IL-2 in serum of patients with different course of condyloma acuminata(CA)in the immune pathogenesis of CA.Methods:solid sandwich Enzyme-Linked Immunoadsorbent assay(ELISA)were performed for detecting the level of IFN-γ,IL-2 in serum of 60 cases with different course of CA.Results:The level of IFN-γ,IL-2 in serum of the group of CA is significantly lower than that of the group of normal control(P0.01),and the level of IFN-γ,IL-2 in serum of the group of long course of CA is significantly lower than that of the group of short course(P0.01).Conclusion:Patients with CA were characterized by the suppressed secretion of the TH1-associated cytokines(eg:IFN-γ,IL-2),this might play an important role in the immune pathogenesis of CA.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the role of the changes of the expression of the level of IFN-γ,IL-2 in serum of patients with different course of condyloma acuminata(CA)in the immune pathogenesis of CA.Methods:solid sandwich Enzyme-Linked Immunoadsorbent assay(ELISA)were performed for detecting the level of IFN-γ,IL-2 in serum of 60 cases with different course of CA.Results:The level of IFN-γ,IL-2 in serum of the group of CA is significantly lower than that of the group of normal control(P0.01),and the level of IFN-γ,IL-2 in serum of the group of long course of CA is significantly lower than that of the group of short course(P0.01).Conclusion:Patients with CA were characterized by the suppressed secretion of the TH1-associated cytokines(eg:IFN-γ,IL-2),this might play an important role in the immune pathogenesis of CA.

Key concepts: Pathogenesis, Immune system, Immunology, Secretion, Interferon γ, Interferon, Interleukin 10, Normal group

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Study on the level of IFN-γ,IL-2 in serum of patients with different course of condyloma acuminata — Research Paper | ScholarLens