2007Zhongguo Yike Daxue xuebaoRequires access

Level of soluble intercellular adhesion molecule-1 in peritoneal fluid of patients with endometriosis

LI Cai-gang

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Abstract

Objective:To investigate the expression of soluble intercellular adhesion molecule-l(sICAM-1)in the peritoneal fluid of patients with endometriosis.Methods:The level of sICAM-1 in the peritoneal fluid of patients with endometriosis(n=21)and normal control subjects(n=10)were determined by enzyme-linked immunosorbent assay.Results:The level of sICAM-1 in patients with endometriosis was significantly higher than that in normal control subjects(P0.05).There was no significant difference in the level of sICAM-1 between patients with stage Ⅰ and Ⅱ endometriosis and those with stage Ⅲ and Ⅳ endometriosis.Conclusion:sICAM-1 may play a role in the pathogenesis of endometriosis.The detection of the level of sICAM-1 in the peritoneal fluid is valuable in the diagnosis and treatment of the patients with endometriosis.

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Objective:To investigate the expression of soluble intercellular adhesion molecule-l(sICAM-1)in the peritoneal fluid of patients with endometriosis.Methods:The level of sICAM-1 in the peritoneal fluid of patients with endometriosis(n=21)and normal control subjects(n=10)were determined by enzyme-linked immunosorbent assay.Results:The level of sICAM-1 in patients with endometriosis was significantly higher than that in normal control subjects(P0.05).There was no significant difference in the level of sICAM-1 between patients with stage Ⅰ and Ⅱ endometriosis and those with stage Ⅲ and Ⅳ endometriosis.Conclusion:sICAM-1 may play a role in the pathogenesis of endometriosis.The detection of the level of sICAM-1 in the peritoneal fluid is valuable in the diagnosis and treatment of the patients with endometriosis.

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Available abstract

Objective:To investigate the expression of soluble intercellular adhesion molecule-l(sICAM-1)in the peritoneal fluid of patients with endometriosis.Methods:The level of sICAM-1 in the peritoneal fluid of patients with endometriosis(n=21)and normal control subjects(n=10)were determined by enzyme-linked immunosorbent assay.Results:The level of sICAM-1 in patients with endometriosis was significantly higher than that in normal control subjects(P0.05).There was no significant difference in the level of sICAM-1 between patients with stage Ⅰ and Ⅱ endometriosis and those with stage Ⅲ and Ⅳ endometriosis.Conclusion:sICAM-1 may play a role in the pathogenesis of endometriosis.The detection of the level of sICAM-1 in the peritoneal fluid is valuable in the diagnosis and treatment of the patients with endometriosis.

Key concepts: Endometriosis, Peritoneal fluid, Pathogenesis, Medicine, Adhesion, Intercellular Adhesion Molecule-1, Intracellular, Stage (stratigraphy)

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