Level of soluble intercellular adhesion molecule-1 in peritoneal fluid of patients with endometriosis
LI Cai-gang
Abstract
LI Cai-gang
Abstract
Objective:To investigate the expression of soluble intercellular adhesion molecule-l(sICAM-1)in the peritoneal fluid of patients with endometriosis.Methods:The level of sICAM-1 in the peritoneal fluid of patients with endometriosis(n=21)and normal control subjects(n=10)were determined by enzyme-linked immunosorbent assay.Results:The level of sICAM-1 in patients with endometriosis was significantly higher than that in normal control subjects(P0.05).There was no significant difference in the level of sICAM-1 between patients with stage Ⅰ and Ⅱ endometriosis and those with stage Ⅲ and Ⅳ endometriosis.Conclusion:sICAM-1 may play a role in the pathogenesis of endometriosis.The detection of the level of sICAM-1 in the peritoneal fluid is valuable in the diagnosis and treatment of the patients with endometriosis.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective:To investigate the expression of soluble intercellular adhesion molecule-l(sICAM-1)in the peritoneal fluid of patients with endometriosis.Methods:The level of sICAM-1 in the peritoneal fluid of patients with endometriosis(n=21)and normal control subjects(n=10)were determined by enzyme-linked immunosorbent assay.Results:The level of sICAM-1 in patients with endometriosis was significantly higher than that in normal control subjects(P0.05).There was no significant difference in the level of sICAM-1 between patients with stage Ⅰ and Ⅱ endometriosis and those with stage Ⅲ and Ⅳ endometriosis.Conclusion:sICAM-1 may play a role in the pathogenesis of endometriosis.The detection of the level of sICAM-1 in the peritoneal fluid is valuable in the diagnosis and treatment of the patients with endometriosis.
Key concepts: Endometriosis, Peritoneal fluid, Pathogenesis, Medicine, Adhesion, Intercellular Adhesion Molecule-1, Intracellular, Stage (stratigraphy)