ScholarLens Back to search
2006•Zhongguo fuyou baojianRequires access

Expression of Soluble Intracellular Adhesion Molecule in Peritoneal Fluid in Patients with Endometriosis

Zhang Han

Open publisher page 0 citations

Abstract

Objective:To study the relationship between intracellular adhesion molecule-1(ICAM-1) and endometriosis.Methods:The expression of sICAM-1 protein were determined by enzyme-linked immunosorbent assays(ELISA) in 30 peritoneal fluid(PF) of patients with endometriosis and 12 PF from normal pelvic cavity/13 PF from non-endometriosis subjects with pelvic adhesion during the same menstrual phase.And then analyzed by F test and t test.Results:The expression of sICAM-1 in PF from patients with endometriosis was significantly higher than those in normal controls,but has no differences with those pelvic adhesion non-endometriosis subjects.Conclusion:The overexpression of sICAM-1 in PF promotes immunotolerance to implanted tissue in the peritoneal environment.In patients with endometriosis,pelvic inflammation may accelerate the developing of endometriosis.

About this research paper

What this paper is about

Objective:To study the relationship between intracellular adhesion molecule-1(ICAM-1) and endometriosis.Methods:The expression of sICAM-1 protein were determined by enzyme-linked immunosorbent assays(ELISA) in 30 peritoneal fluid(PF) of patients with endometriosis and 12 PF from normal pelvic cavity/13 PF from non-endometriosis subjects with pelvic adhesion during the same menstrual phase.And then analyzed by F test and t test.Results:The expression of sICAM-1 in PF from patients with endometriosis was significantly higher than those in normal controls,but has no differences with those pelvic adhesion non-endometriosis subjects.Conclusion:The overexpression of sICAM-1 in PF promotes immunotolerance to implanted tissue in the peritoneal environment.In patients with endometriosis,pelvic inflammation may accelerate the developing of endometriosis.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To study the relationship between intracellular adhesion molecule-1(ICAM-1) and endometriosis.Methods:The expression of sICAM-1 protein were determined by enzyme-linked immunosorbent assays(ELISA) in 30 peritoneal fluid(PF) of patients with endometriosis and 12 PF from normal pelvic cavity/13 PF from non-endometriosis subjects with pelvic adhesion during the same menstrual phase.And then analyzed by F test and t test.Results:The expression of sICAM-1 in PF from patients with endometriosis was significantly higher than those in normal controls,but has no differences with those pelvic adhesion non-endometriosis subjects.Conclusion:The overexpression of sICAM-1 in PF promotes immunotolerance to implanted tissue in the peritoneal environment.In patients with endometriosis,pelvic inflammation may accelerate the developing of endometriosis.

Key concepts: Endometriosis, Peritoneal fluid, Medicine, Peritoneal cavity, Adhesion, Pelvic endometriosis, Intercellular Adhesion Molecule-1, Intracellular

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Expression of Soluble Intracellular Adhesion Molecule in Peritoneal Fluid in Patients with Endometriosis — Research Paper | ScholarLens