Study on serum LAM-IgG for the diagnosis of tuberculosis

Objective:To investigate the value of LAM-IgG in the diagnosis,differential diagnosis and prognosis judgment of tuberculosis so as to provide a basis for diagnosis and treatment of tuberculosis.Methods:The LAM-IgG in serum were detected with Enzyme-linked immunosorbent assay(ELISA).SPSS13.0 statistical software was used for data statistics.Results:The positive rate of LAM-IgG in active pulmonary tuberculosis,non-active pulmonary tuberculosis,extra-pulmonary tuberculosis and the control group were 88.5%,28.6%,83.3%,3.2%,respectively.The positive rate of LAM-IgG in the case group was higher than the control group(P0.05).The positive rates of LAM-IgG in active pulmonary tuberculosis group and extra-pulmonary were higher than non-active tuberculosis(P0.05).The sensitivity,specificity,accuracy of LAM-IgG in the diagnosis of active pulmonary tuberculosis and extra-pulmonary tuberculosis groups were 86.4%,83.3%,90.7%.Conclusion:LAM-IgG have a higher sensitivity,specificity,accuracy in the diagnosis of active pulmonary tuberculosis and extra-pulmonary tuberculosis.It can be used as an indicator of diagnosis,differential diagnosis and prognosis judgment of tuberculosis in the active pulmonary and extra-pulmonary tuberculosis.