2009•Pharmaceutical and Clinical ResearchRequires access
Therapeutic effect of different doses of batroxobin combined with edaravone on the patients with progressive cerebral infarction
Xiaoling Yuan
Open publisher page 0 citations
Abstract
Objective: To observe therapeutic effect of different doses of batroxobin combined with edaravone on the patients with progressive cerebral infarction.Methods: 90 patients with progressive cerebral infarction were randomly divided into normal dose batroxobin group(control group),normal dose batroxobin combined with edaravone group(normal combined group) and uncommon dose batroxobin combined with edaravone group(uncommon combined group).Neurological deficit scores(NDS) were evaluated before treatment,and 7 days and 14 days after treatment.Fibrinogen(FIB) was determined before treatment and 3 days and 7 days after treatment.Results: Effective rate and notable effective rate of normal combined group after 14 days of treatment were 90% and 67%,and 97%,77% of uncommon combined group,which were both obviously higher than those of control group 90% and 27%.Effective rate and notable effective rate of uncommon combined group were higher than those of normal combined group,but the difference was not significantly.Conclusion: The treatment of batroxobin combined with edaravone on progressive cerebral infarction is effective and safe.