2003•Journal of Jilin University ofRequires access

Expression of Leukaemia Inhibitory Factor in Endometrial of the Patients with Unexplained Infertility

Song Zhang

Abstract

Objective:To investigate the expression of leukaemia inhibitory factor (LIF) in endometrial of patients with unexplained infertility. Methods:By a quantitative reverse transcription polymerase chain reaction (RT PCR),the expression of LIF in endometrium during mid luteal phase in 30 cases infertility group (unexplained infertility) and 20 cases control group was detected. Results:The level of LIF mRNA expression on endometrium during mid luteal phase in infertility group was 0.426±0.108,significantly lower than those in the control group. Conclusion:The decreased expression of LIF may be one of the major causes of unexplained infertility. [

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Key concepts: Unexplained infertility, Infertility, Endometrium, Luteal phase, Medicine, Andrology, Leukemia inhibitory factor, Gynecology