Clinical Analysis of Index of Bone Metabolism Changes in Maintained Hemodialysis Patients

Aim To investigate the levels of calcium and phosphorus disturbance and intact parathyroid hormone( iPTH) in maintained hemodialysis( HD) patients.Methods The study included 98 patients,who were on haemodialysis treatment for 3~192 months.Patients in a group were subdivided into dialysis age 12 months group and 12months dialysis age 36 months group and dialysis age ≥36 months group.iPTH level and clinical data were compared among the groups.Results Serum iPTH was significantly higher in dialysis age ≥36 months group than that in dialysis age 12 months group and 12 months dialysis age 36 months group( P 0.05).iPTH level was significantly lower in diabetic patients with short dialysis age( dialysis age 36 months) than that in nondiabetic patients( P 0.05).Multivariable regression analysis showed that there were correlation between iPTH and dialysis age,serum phosphorus.Conclusion iPTH level increases in patients with longer dialysis age.