Cinical Study on Comprehensive Treatment of Esophageal Carcinoma

Objective To investigate the comprehensive treatment methods of esophageal carcinoma.Methods The 254 patients with esophageal carcinoma were randomly divided into three groups.The 102 patients were given radiotherapy(group RT).The 60 patients were treated with conformal radiotherapy combined with chemotherapy from the 1st and 5th week of chemotherapy(group CRT).The 92 patients were treated with radiotherapy combined with chemotherapy plus traditional Chinese medicine from the 1st and 5th week of chemotherapy(Combined group).Results The end time of follow-up was December 2006.In Group RT,Group CRT and Combined group,the incidence rates of hematopoietic toxicity were observed in 25.5%,90% and 54.3% of patients respectively,acute radiation esophagitis occurred in 94.1%,96.7%and 21.7% of patients respectively,and radiation pneumonitis occurred in 11.8%,26.7% and 4% of patients respectively.The 1-,2-,3-year survival rates were 43.1%,50% and 71.7%,33.3%,40% and 56.5%,13.7%,27% and 39.1%,respectively.Conclusion The primary research result suggest that the conformal radiotherapy combined with chemotherapy plus traditional Chinese medicine is superior to the radiotherapy along or conformal radiotherapy combined with chemotherapy in improving the living quality,short-term curative effect and 1-,2-year survival rates.The side effects are tolerable.