Analysis of Clinical Features in Chinese Patients with Moyamoya Disease

Objective To explore of the clinical features in patients with moyamoya disease in the P. R. China. Methods The age of onset, gender, symptoms, images and revascularization of 54 Chinese patients with moyamoya disease were analyzed and compared with the data of the patients with moyamoya disease in the other countries. Results The age distribution among Chinese patients showed two peaks that were similar to those among Japanese and Korean patients. However, the incidence of male adult patients with moya-moya disease in China was higher than those in Japan and Korea. The incidence of cerebral infarction was higher, whereas transient ischemic attack and seizure were lower in Chinese patients than those in Japanese patients. The incidence of cerebral hemorrhage was similar to that in Japanese patients, and most of the patients with cerebral hemorrhage were females. The outcomes of treatment were not different between Chinese and Japanese patients. Conclusions The clinical features and pathogenetic mechanism of moyamoya disease in Chinese may be different from those in the people of the other countries.[