Clinical Features of Moyamoya Disease Complicated with Posterior Circulation Lesions

Objective To explore the epidemiological and clinical characteristics of moyamoya disease complicated with posterior circulation lesions and to improve awareness of moyamoya disease.Methods The data of 252 patients with moyamoya disease complicated with posterior circulation lesions during Jan.2002 and Jan.2010 were retrospectively analyzed.Results Among the 252 patients,46 patients were less than 10 years old(18.3%),47 patients were 10～18 years old(18.6%),159 patients were older than or equal to 18 years old(63.1%).There were two disease peaks in the age distribution,with the highest peak at 10 to 14 years of age,another peak at 40 to 44 years of age.There were no significant differences between the male and female patients in terms of the age distribution curves.In distribution of the regions,57 patients were from Henan Province,42 patients from Shangdong Province and 35 patients from Hebei Province.The remaining patients were distributed among the other 27 provinces and municipalities.19 patients(7.5%) had familial inheritance history.This group of patients were first admitted for with TIA,cerebral infarction,headaches,dizziness,cerebral hemorrhage,and epilepsy.They were identified by the cerebral angiogram or MRA tests.Conclusion The epidemiology and clinical characteristics of lesions moyamoya disease complicated with posterior circulation lesions are unique.Suspected cases should take cerebral angiogram or MRA for early diagnosis and treatment.