Clinical effects of cefminox on treating lower respiratory tract infections in patients with chronic obstructive pulmonary diseases

OBJECTIVE To observe the efficacy and safety of cefminox in the treatment of lower respiratory tract infection patients with chronic obstructive pulmonary diseases.METHODS A total of 56 patients with lower respiratory tract infection with chronic obstructive pulmonary diseases in our hospital from Aug 2009 to Aug 2010 were randomizedly divided into two groups,with 28 cases in each group.Based on the routine therapy,patients were assigned to receive cefminox 2 g,ivgtt,2 times/day,for 7-14 days in the treatment group,and oeftazidine 2 g,ivgtt,2 times/day,for 7-14 days in the control group.RESULTS The cure rate,the effective rate and the bacterial clearance rate were 78.6%,92.9% and 93.1% in the treatment group,and 53.6%,71.4% and 66.7% in the control group,with significant difference between the two groups.CONCLUSION Cefminox is effective and safe in the treatment of lower respiratory tract infections of patients with chronic obstructive pulmonary diseases and has high bacterial eradication rate.