ScholarLens Back to search
2012•Journal of Chengdu University of Traditional Chinese MedicineRequires access

Mechanism of Electroacupuncture Improvement to the Fatigue and Pain Threshold in Chronic Fatigue Rats

Quan Yuan

Open publisher page 0 citations

Abstract

Objective:To explore the effect of electroacupuncture of behavior changes in chronic fatigue rats and the mechanism.Methods:96 SD rats were randomly divided into normal group,model group,model electroacupuncture group(EA group),sham injection group(SI group),CRF injection group(CRF group),CRF injection and electroacupuncture group(CRFEA group),CRFA injection group(CRFA group),CRFA injection and electroacupuncture group(CRFAEA group).All the rats except the normal group rats were restrainted and swam in cool water.The rats in the CRF group,CRFEA group,CRFA group and CRFAEA group were intracerebroventricular injected.The rats in the SI group were sham intracerebroventricular injected.The rats in the EA group,CRFEA group and CRFAEA group were treated by electroacupuncture on BL23,ST36.The exhaustive swimming time,Finding the platform time of Morris water maze test and reaction time to pain were tested.Results:After modeling,comparison with normal group,the exhaustive swimming time and reaction time to pain in the other groups were significantly shorter(P0.05),and the finding the platform time were significantly longer(P0.05).After treatment,comparison with model group,the exhaustive swimming time and reaction time to pain in EA groups and CRFEA group were significantly longer(P0.05),and the finding the platform time were significantly shorter(P0.05).Conclusion:Electroacupuncture can alleviate physical and mental fatigue and improve pain threshold in chronic fatigue rats.The CRH in hypothalamus is important to electroacupuncture.

About this research paper

What this paper is about

Objective:To explore the effect of electroacupuncture of behavior changes in chronic fatigue rats and the mechanism.Methods:96 SD rats were randomly divided into normal group,model group,model electroacupuncture group(EA group),sham injection group(SI group),CRF injection group(CRF group),CRF injection and electroacupuncture group(CRFEA group),CRFA injection group(CRFA group),CRFA injection and electroacupuncture group(CRFAEA group).All the rats except the normal group rats were restrainted and swam in cool water.The rats in the CRF group,CRFEA group,CRFA group and CRFAEA group were intracerebroventricular injected.The rats in the SI group were sham intracerebroventricular injected.The rats in the EA group,CRFEA group and CRFAEA group were treated by electroacupuncture on BL23,ST36.The exhaustive swimming time,Finding the platform time of Morris water maze test and reaction time to pain were tested.Results:After modeling,comparison with normal group,the exhaustive swimming time and reaction time to pain in the other groups were significantly shorter(P0.05),and the finding the platform time were significantly longer(P0.05).After treatment,comparison with model group,the exhaustive swimming time and reaction time to pain in EA groups and CRFEA group were significantly longer(P0.05),and the finding the platform time were significantly shorter(P0.05).Conclusion:Electroacupuncture can alleviate physical and mental fatigue and improve pain threshold in chronic fatigue rats.The CRH in hypothalamus is important to electroacupuncture.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To explore the effect of electroacupuncture of behavior changes in chronic fatigue rats and the mechanism.Methods:96 SD rats were randomly divided into normal group,model group,model electroacupuncture group(EA group),sham injection group(SI group),CRF injection group(CRF group),CRF injection and electroacupuncture group(CRFEA group),CRFA injection group(CRFA group),CRFA injection and electroacupuncture group(CRFAEA group).All the rats except the normal group rats were restrainted and swam in cool water.The rats in the CRF group,CRFEA group,CRFA group and CRFAEA group were intracerebroventricular injected.The rats in the SI group were sham intracerebroventricular injected.The rats in the EA group,CRFEA group and CRFAEA group were treated by electroacupuncture on BL23,ST36.The exhaustive swimming time,Finding the platform time of Morris water maze test and reaction time to pain were tested.Results:After modeling,comparison with normal group,the exhaustive swimming time and reaction time to pain in the other groups were significantly shorter(P0.05),and the finding the platform time were significantly longer(P0.05).After treatment,comparison with model group,the exhaustive swimming time and reaction time to pain in EA groups and CRFEA group were significantly longer(P0.05),and the finding the platform time were significantly shorter(P0.05).Conclusion:Electroacupuncture can alleviate physical and mental fatigue and improve pain threshold in chronic fatigue rats.The CRH in hypothalamus is important to electroacupuncture.

Key concepts: Electroacupuncture, Medicine, Anesthesia, Threshold of pain, Normal group, Internal medicine, Acupuncture, Pathology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Mechanism of Electroacupuncture Improvement to the Fatigue and Pain Threshold in Chronic Fatigue Rats — Research Paper | ScholarLens