2014Shiyong yaowu yu linchuangRequires access

Advanced research in statins-related myopathy

Xiaomin Du

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Abstract

As statins were widely used in clinic,statins-related myopathy,especially rhabdomyolysis,had drawn wide attention at home and abroad. In this paper,we analyzed and reviewed their muscle toxicity,and also discussed the clinical manifestations,pathogenic mechanism,prevention and treatment measures of statins-related myopathy,in order to promote the rational use of statins,and provide reference for clinical practice.

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What this paper is about

As statins were widely used in clinic,statins-related myopathy,especially rhabdomyolysis,had drawn wide attention at home and abroad. In this paper,we analyzed and reviewed their muscle toxicity,and also discussed the clinical manifestations,pathogenic mechanism,prevention and treatment measures of statins-related myopathy,in order to promote the rational use of statins,and provide reference for clinical practice.

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Available abstract

As statins were widely used in clinic,statins-related myopathy,especially rhabdomyolysis,had drawn wide attention at home and abroad. In this paper,we analyzed and reviewed their muscle toxicity,and also discussed the clinical manifestations,pathogenic mechanism,prevention and treatment measures of statins-related myopathy,in order to promote the rational use of statins,and provide reference for clinical practice.

Key concepts: Myopathy, Rhabdomyolysis, Medicine, Clinical Practice, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Statin, Intensive care medicine, Physical therapy

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