Study on hematoblastic activation function in patients with unstable angina
Meng Li
Abstract
Meng Li
Abstract
Objective To investigate the effect of platelet activation in unstable angina(UA).Methods The expression levels of platelet surface glycoprotein,including CD63,CD42b and PAC-1,were accurately detected by flow cytometry in patients with UA.Results The expression level of CD63,PAC-1 of platelet surface glycoprotein in patients with UA was significantly up-regulated when compared with healthy people,while CD42b expression down-regulated,there was significant difference(P0.01).Conclusion The platelet activation in patients with UA is in an activated state,which is involved in the development of UA.
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Objective To investigate the effect of platelet activation in unstable angina(UA).Methods The expression levels of platelet surface glycoprotein,including CD63,CD42b and PAC-1,were accurately detected by flow cytometry in patients with UA.Results The expression level of CD63,PAC-1 of platelet surface glycoprotein in patients with UA was significantly up-regulated when compared with healthy people,while CD42b expression down-regulated,there was significant difference(P0.01).Conclusion The platelet activation in patients with UA is in an activated state,which is involved in the development of UA.
Key concepts: Medicine, CD63, Platelet activation, Platelet, Platelet membrane glycoprotein, Flow cytometry, Cardiology, Internal medicine