Study on the clinical use of insulin lispro

Objective: To evaluate the efficacy and safety of insulin lispro in the treatment of diabetic patients. Methods: Blood glucose, HbA1c, dose of insulin lispro and incidence of hypoglycemia were assessed in 57 patients with diabetes, be-fore and after treatment with insulin lispro, during the period from January to November 2007. Results: Three months after treatment with insulin lispro, fasting blood glucose, 2 h postprandial glucose and HbA1c were significantly lower, compared with baseline. The total daily dose of insulin lispro is similar with or slightly less than that of previously used recombinant human insulin; meanwhile, the incidence of hypoglycemia significantly decreased. Conclusion: Insulin lispro provides bet-ter glycemic control with lower incidence of hypoglycemia, and so compliance, of the diabetic patients.