2015Northwest Pharmaceutical JournalRequires access

Study on quality standard of Yiqihuoxue Tablets

Wei Xiangfen

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Abstract

Objective To establish the quality standard for Yiqihuoxue Tablets.Methods Astragali Radix,Angelicae sinensis Radix,Paeoniae Radix Rubra and Chuanxiong Rhizomain the prescription were identified by TLC.HPLC-ELSD was adopted for the quantative analysis of astragaloside A which is an effective component of the formula.Results The TLC of Astragalus Radix,Angelicae sinensis Radix,Paeoniae Radix Rubra and Chuanxiong Rhizoma showed good specificity.Astragaloside A showed good linearity over the range of 0.538-26.9μg(r=0.999 9)and the average recovery was 98.9%,RSD=1.8%(n=6).Conclusion The method can be used for the preparation quality control.

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Objective To establish the quality standard for Yiqihuoxue Tablets.Methods Astragali Radix,Angelicae sinensis Radix,Paeoniae Radix Rubra and Chuanxiong Rhizomain the prescription were identified by TLC.HPLC-ELSD was adopted for the quantative analysis of astragaloside A which is an effective component of the formula.Results The TLC of Astragalus Radix,Angelicae sinensis Radix,Paeoniae Radix Rubra and Chuanxiong Rhizoma showed good specificity.Astragaloside A showed good linearity over the range of 0.538-26.9μg(r=0.999 9)and the average recovery was 98.9%,RSD=1.8%(n=6).Conclusion The method can be used for the preparation quality control.

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Available abstract

Objective To establish the quality standard for Yiqihuoxue Tablets.Methods Astragali Radix,Angelicae sinensis Radix,Paeoniae Radix Rubra and Chuanxiong Rhizomain the prescription were identified by TLC.HPLC-ELSD was adopted for the quantative analysis of astragaloside A which is an effective component of the formula.Results The TLC of Astragalus Radix,Angelicae sinensis Radix,Paeoniae Radix Rubra and Chuanxiong Rhizoma showed good specificity.Astragaloside A showed good linearity over the range of 0.538-26.9μg(r=0.999 9)and the average recovery was 98.9%,RSD=1.8%(n=6).Conclusion The method can be used for the preparation quality control.

Key concepts: Radix (gastropod), Quality standard, Chromatography, High-performance liquid chromatography, Traditional medicine, Chemistry, Astragaloside, Medicine

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