Clinical Analysis for Hepatic Lesion During Anti-tuberculosis Treatment in AIDS Patients Complicated with Tuberculosis

Objective To investigate the problem and the risk factors of hepatic lesion in AIDS patients complicated with tuberculosis during the initial phase of anti-tuberculosis treatment.Methods The clinical data of 70 AIDS patients complicated with tuberculosis(the case group) and 98 simple tuberculosis patients(the control group) were retrospectively analyzed.We compared the rates of hepatic lesion between the two groups and investigated the risk factors of hepatic lesion during first two months after initiation of anti-tuberculosis treatment.Results 16(22.8%) patients suffered hepatic lesion in the case group and 12(12.2%) patients suffered hepatic lesion in the control group,it showed no significant difference between those group(χ2=3.311,P=0.069).Otherwise,the comparison for the degree of hepatic lesion and the time of development of hepatic lesion were also not significantly different in those groups(P0.05).Conclusions AIDS patients complicated with tuberculosis might not be the risk factor of development of hepatic lesion during the initial phase of anti-tuberculosis treatment.And it shows no significant correlation between the severity of hepatic lesion and complicated withAIDS in the study.