2012Chinese Journal of General PracticeRequires access

Analysis of Pituitary Adenoma Microsurgical Treatment in 26 Cases

Tang De-gang

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Abstract

Objective To study the technique and experience of single-nostril transsphenoidal pituitary adenoma microsurgery.Methods Clinical data of 26 patients undergoing transsphenoidal microsurgery for pituitary adenomas was analyzed,the surgical approach,operation and treatment of complications were evaluated.Results Among the 26 cases,10 cases were PRL adenoma,6 cases were GH adenoma,mixed type 2 cases and no functional adenoma 7 cases.18 cases accepted total resection,5 cases sub-total resection and 3 cases most tumors resection.After surgery,electrolyte imbalance occurred in 1 cases,transient diabetes insipidus in 5 cases and no permanent diabetes insipidus,2 cases with CSF rhinorrhea lasting for two weeks and needing no reoperation.Conclusion Compared with craniotomy for pituitary tumor resection surgery,transsphenoidal surgery significantly reduced mortality and disability rates,which was the preferred approach for the treatment of pituitary tumors.Strictly grasp the good surgical indications and contraindications,which can make the surgical treatment of pituitary tumors to achieve a satisfactory therapeutic effect.

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Objective To study the technique and experience of single-nostril transsphenoidal pituitary adenoma microsurgery.Methods Clinical data of 26 patients undergoing transsphenoidal microsurgery for pituitary adenomas was analyzed,the surgical approach,operation and treatment of complications were evaluated.Results Among the 26 cases,10 cases were PRL adenoma,6 cases were GH adenoma,mixed type 2 cases and no functional adenoma 7 cases.18 cases accepted total resection,5 cases sub-total resection and 3 cases most tumors resection.After surgery,electrolyte imbalance occurred in 1 cases,transient diabetes insipidus in 5 cases and no permanent diabetes insipidus,2 cases with CSF rhinorrhea lasting for two weeks and needing no reoperation.Conclusion Compared with craniotomy for pituitary tumor resection surgery,transsphenoidal surgery significantly reduced mortality and disability rates,which was the preferred approach for the treatment of pituitary tumors.Strictly grasp the good surgical indications and contraindications,which can make the surgical treatment of pituitary tumors to achieve a satisfactory therapeutic effect.

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Available abstract

Objective To study the technique and experience of single-nostril transsphenoidal pituitary adenoma microsurgery.Methods Clinical data of 26 patients undergoing transsphenoidal microsurgery for pituitary adenomas was analyzed,the surgical approach,operation and treatment of complications were evaluated.Results Among the 26 cases,10 cases were PRL adenoma,6 cases were GH adenoma,mixed type 2 cases and no functional adenoma 7 cases.18 cases accepted total resection,5 cases sub-total resection and 3 cases most tumors resection.After surgery,electrolyte imbalance occurred in 1 cases,transient diabetes insipidus in 5 cases and no permanent diabetes insipidus,2 cases with CSF rhinorrhea lasting for two weeks and needing no reoperation.Conclusion Compared with craniotomy for pituitary tumor resection surgery,transsphenoidal surgery significantly reduced mortality and disability rates,which was the preferred approach for the treatment of pituitary tumors.Strictly grasp the good surgical indications and contraindications,which can make the surgical treatment of pituitary tumors to achieve a satisfactory therapeutic effect.

Key concepts: Medicine, Diabetes insipidus, Microsurgery, Pituitary adenoma, Surgery, Craniotomy, Transsphenoidal surgery, Adenoma

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