A study on urogenital mycoplasma infection and its drug resistance

Objective To investigate urogenital mycoplasma infection and drug sensitivity situation in our hospital during Janury 2009 and June 2010.Methods Mycoplasma was cultivated and its antibiotic susceptibility was tested with Mycoplasma YIN KE reagent box.Results 440 cases were found positive mycoplasma among 1080 cases,accouting for 40.7% of all cases.Among the 440 clinical isolates,356 cases were Ureaplasma urealyticun(Uu) positive(80.9%),46 cases with Uu and Mh complicated infection positive(10.4%),38 cases with Mh positive(8.6%).The results of drug sensitivity test showed that the most sensitive antibiotics were doxycyline josamycin and minocyline,and the second most antibiotics were clarithromycin and azithromycin.The drug sensitivity for ofloxacin,spafloxacin and roxthromycin were found low.Conclusion Ureaplsm urealyticum is the main source of urogenttal mycoplasma infection.doxycyline and josamycin could be selected as major drugs to treat mycopalsma infection.