Relationship between procalcitonin and ARDS in patients with severe multiple trauma

Objective To study the change of serum procalcitonin in patients with multiple trauma,and determine its relationship with the severity of trauma infection and ARDS.Methods The levels of serum procalcitonin was detected 1,3,7d after trauma in 33 cases respectively.The values of ISS,APACHEⅡ were also determined.Meanwhile,the incidence of infection and ARDS were recorded.Results The level of serum procalcitonin in patients with multiple trauma 24h after injury was much higher than that of normal controls(P0.01),and was positively correlated with APACHEⅡ(r_(s)=0.601,P0.05).The level of serum procalcitonin and the values of APACHE Ⅱ in patients with ARDS was much higher than that of normal organ function group(P0.05).Conclusion Serum procalcitonin might increase in patients with trauma,which is positively correlated with the severity of trauma.Dynamic measurement of procalcitonin may help to discover the infection earlier.Procalcitonin is a parameter warning of ARDS.