Clinical Analysis of the Treatment of Anovulation Patients with Polycystic Ovary Syndrome by Letrozole Combined with Traditional Chinese Medicine

Objective:To study the clinical effects of the treatment of anovulation patients with polycystic ovary syndrome(PCOS) by letrozole(LE) combined with traditional Chinese medicine.Methods: 60 anovulation patients in kidney-type of TCM were randomly divided into two groups,one treatment group and one control group.30 patients in the treatment group were treated with letrozole combined with traditional Chinese medicine while 30 patients in the control group were simply treated with letrozole.A menstrual cycle was a course of treatment.The menstruation,ovulation,endometrial,and pregnancy in the two groups were observed for six months.Results:(1) Menstruation and symptoms improvement: 28 cases in the treatment group were effective,and 2 cases ineffective;but in the control group,22 cases effective,8 cases ineffective.(2) Ovulation: the ovulation rate in the treatment group was 96.67%;the ovulation rate in control group was 93.33%.(3) Intima improvement: Period A,B,C in the treatment was 60%,20% and 20% respectively;Period A,B,C in the control group was 30.00%,23.33%,and 46.67% respectively.(4) Pregnancy: The pregnancy rate in the treatment group was 73.33%;the pregnancy rate in the control group was 56.67%.Conclusion: Letrozole combined with traditional Chinese medicine shows a good curative effect on the treatment of the anovulation patients with polycystic ovary syndrome and can induce the development of a single dominant follicle,and improve the pregnancy rate.