Observation of the therapeutic effect of somatostatin and octreotide in treating acute pancreatitis

Objective To evaluate the curative effects of somatostatin and octreotide in the treatment of acute pancreastitis.Methods 67 cases of patients with acute pancreastitis were randomly divided into two groups,the treatment group(35 cases),including 13 served acute pancrestitis(SAP)received somatostatin,and the contort group(32 cases),including 11 cases served acute pancreatitis(SAP)were treated by octreotide.The effects and syndrome of each group were observed after the treatment.Results Patients in the group of AP treated by somatostatin have completely recovered at average of 4.6 days,with one patient being followed by the treatment of operation.The patients in the octreotide have completly recovered at 5.1 days,with a patient being operated on,and one got hydrothorax.Both the treatment group and the contort group have closely same clinical therapy effect.Conclusion A stable effect can be attained through somatostatin and octreotide for treatment of acute pancereatitis.It can also shorten the time of treatment,reduce syndrome,cut down the death rate and increase the chance of taking operation.