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Uncertainty Analysis Assay for Cefalexin Capsules with HPLC

Wang Zheng-yu

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Abstract

Objective To establish a HPLC method for uncertainty analysis of Cefalexin Capsules.Methods The calculation formula of uncertainty was deduced in the procedure of determination the content in Capsules.Each active components of uncertainty was calculated the variable parameters among the procedures.The combined uncertainty and extended uncertainty and confidence was finally obtained by synthesized the uncertainties of various component variables.Results The mathematic model of uncertainty is establish for applicable to cvaluate the accuracy of assay of puerain injection.Conclusion The mathematic model of uncertainty of measureme establish is reasonable and reliable,it is applicable to evaluate accuracy of assay for the capsules with HPLC.

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What this paper is about

Objective To establish a HPLC method for uncertainty analysis of Cefalexin Capsules.Methods The calculation formula of uncertainty was deduced in the procedure of determination the content in Capsules.Each active components of uncertainty was calculated the variable parameters among the procedures.The combined uncertainty and extended uncertainty and confidence was finally obtained by synthesized the uncertainties of various component variables.Results The mathematic model of uncertainty is establish for applicable to cvaluate the accuracy of assay of puerain injection.Conclusion The mathematic model of uncertainty of measureme establish is reasonable and reliable,it is applicable to evaluate accuracy of assay for the capsules with HPLC.

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Available abstract

Objective To establish a HPLC method for uncertainty analysis of Cefalexin Capsules.Methods The calculation formula of uncertainty was deduced in the procedure of determination the content in Capsules.Each active components of uncertainty was calculated the variable parameters among the procedures.The combined uncertainty and extended uncertainty and confidence was finally obtained by synthesized the uncertainties of various component variables.Results The mathematic model of uncertainty is establish for applicable to cvaluate the accuracy of assay of puerain injection.Conclusion The mathematic model of uncertainty of measureme establish is reasonable and reliable,it is applicable to evaluate accuracy of assay for the capsules with HPLC.

Key concepts: Cefalexin, Medicine, Uncertainty analysis, Standard uncertainty, Measurement uncertainty, High-performance liquid chromatography, Chromatography, Statistics

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