ScholarLens Back to search
2009•Yaowu fenxi zazhiRequires access

Evaluation of uncertainty measurement in content determination of cefalexin capsules by HPLC

Shen An

Open publisher page 0 citations

Abstract

Objective:To establish a method for the evaluation of the uncertainty in the content determination of cefalexil in cefalexin capsules by HPLC.Method:Each components of uncertainty was calculated by analyzing the various variable parameters among the procedures.The combined standard uncertainty uc and the expanded uncertainty U95were then finally obtained by synthesizing the uncertainties of various component variables.Rusults:The expression of the results of the content determination of cefalexin capsules was 101.7%±3.26%(k=2),the combined standard uncertainty uc was1.63%,the expanded uncertainty U95was 3.26%.Conclusion:The method of the evaluation of uncertainty measurement established in this paper is reasonable and reliable.

About this research paper

What this paper is about

Objective:To establish a method for the evaluation of the uncertainty in the content determination of cefalexil in cefalexin capsules by HPLC.Method:Each components of uncertainty was calculated by analyzing the various variable parameters among the procedures.The combined standard uncertainty uc and the expanded uncertainty U95were then finally obtained by synthesizing the uncertainties of various component variables.Rusults:The expression of the results of the content determination of cefalexin capsules was 101.7%±3.26%(k=2),the combined standard uncertainty uc was1.63%,the expanded uncertainty U95was 3.26%.Conclusion:The method of the evaluation of uncertainty measurement established in this paper is reasonable and reliable.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To establish a method for the evaluation of the uncertainty in the content determination of cefalexil in cefalexin capsules by HPLC.Method:Each components of uncertainty was calculated by analyzing the various variable parameters among the procedures.The combined standard uncertainty uc and the expanded uncertainty U95were then finally obtained by synthesizing the uncertainties of various component variables.Rusults:The expression of the results of the content determination of cefalexin capsules was 101.7%±3.26%(k=2),the combined standard uncertainty uc was1.63%,the expanded uncertainty U95was 3.26%.Conclusion:The method of the evaluation of uncertainty measurement established in this paper is reasonable and reliable.

Key concepts: Cefalexin, Standard uncertainty, Chemistry, Measurement uncertainty, Chromatography, Content (measure theory), High-performance liquid chromatography, Relative standard deviation

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Evaluation of uncertainty measurement in content determination of cefalexin capsules by HPLC — Research Paper | ScholarLens