Solitary Fibrous Tumor: CT Findings and Pathological Features
Yang Xiao-fen
Abstract
Yang Xiao-fen
Abstract
Purpose To investigate the multi-slice spiral CT(MSCT) findings and pathological features of solitary fibrous tumor(SFT). Materials and Methods A retrospective study was conducted on the MSCT findings of six cases of SFT proved pathologically, two located in the thoracic walls, one in the breast, one in the abdominal cavity, one in the inferior abdominal wall, and one in the pelvic cavity. The MSCT findings were further compared with pathological results. Results All the six cases presented solitary masses with well-defined margin, among which one was round-like and fve were lobulated. On plain CT scans, one showed homogeneous density, two with necrosis or cystic degeneration, and three with calcifcation. On enhanced CT scans, one displayed homogeneous intensity, five heterogeneous intensity with lichenoid shape,two with hypertrophic tumor vessels, all presenting afast-in and slow-outordelayed enhancementpattern. Tumor tissues mainly consisted of collagen fbers and spindle cells in different hyperplastic degrees under microscope, with cell enriched area alternating with less cell area, interstitial keloid hyaline degeneration, enlarged collagen bundle, and enriched interstitial vessels. Conclusion The MSCT fndings of SFT can be expressed as isolated mass with well-defned margin, after enhancement, it presents image features such as heterogeneous intensity with lichenoid shape, and patterns such asfast-in and slowoutordelayed enhancement. Combined with immunohistochemical test, they can be used as clinical evidence for the diagnosis of SFT.
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Purpose To investigate the multi-slice spiral CT(MSCT) findings and pathological features of solitary fibrous tumor(SFT). Materials and Methods A retrospective study was conducted on the MSCT findings of six cases of SFT proved pathologically, two located in the thoracic walls, one in the breast, one in the abdominal cavity, one in the inferior abdominal wall, and one in the pelvic cavity. The MSCT findings were further compared with pathological results. Results All the six cases presented solitary masses with well-defined margin, among which one was round-like and fve were lobulated. On plain CT scans, one showed homogeneous density, two with necrosis or cystic degeneration, and three with calcifcation. On enhanced CT scans, one displayed homogeneous intensity, five heterogeneous intensity with lichenoid shape,two with hypertrophic tumor vessels, all presenting afast-in and slow-outordelayed enhancementpattern. Tumor tissues mainly consisted of collagen fbers and spindle cells in different hyperplastic degrees under microscope, with cell enriched area alternating with less cell area, interstitial keloid hyaline degeneration, enlarged collagen bundle, and enriched interstitial vessels. Conclusion The MSCT fndings of SFT can be expressed as isolated mass with well-defned margin, after enhancement, it presents image features such as heterogeneous intensity with lichenoid shape, and patterns such asfast-in and slowoutordelayed enhancement. Combined with immunohistochemical test, they can be used as clinical evidence for the diagnosis of SFT.
Key concepts: Medicine, Solitary fibrous tumor, Pathological, Hyaline, Pathology, Lumen (anatomy), Homogeneous, Radiology