Study of heart rate turbulence and heart rate variability in patients with isolated systolic hypertension

Objective:To observe the change of the heart rate turbulence(HRT)and heart rate variability(HRV)in patients with isolated systolic hypertension(ISH).Method:Eighty-five patients with isolated systolic hypertension(ISH),80 patients with common hypertension and 58 control subjects were investigated.Turbulence onset(TO),turbulence slope(TS),SDNN,pNN50 and LF/HF were measured by using recorded 24 hours dynamic electrocardiogram.The difference of the groups were compared,and the correlation between the groups were analyzed.Result:HRT and HRV were significantly different between hypertension groups(ISH and common hypertension)and control group(P0.05).TS and LF/HF were significantly lower in ISH group than in common hypertension group(P0.05).Good correlations were found between the HRT parameters and HRV parameters.The correlation coefficient between pNN50 and TO/TS were most highest.Conclusion:HRT and HRV in patients with primary hypertension are significantly abnormal and they are more significant in patients with ISH than in patients with common hypertension.And there is a strong correlation between HRT and HRV.It suggested that the cardiac autonomic nerves dysfunction perhaps has an important influence on hypertension generation and prognosis.