Observation on different blood purification modes for multiple organ dysfunction syndrome patients associated with acute renal failure

Objective:To investigate the efficacy of hemoperfusion(HP) with continuous blood purification(CBP) on patients suffered from multiple organs failure with acute renal failure and its mechanism.Methods:40 patients were divided into two groups randomly,one group received continuous blood purification treatment only,and the other group was received HP with CBP treatment.Comparison of the change of APACHEⅡscore and the level of BUN,Cr,TNF-α and IL-6 before and after treatment was made.Results:After treatment,the clinical symptoms of patients in both two groups were improved,the APACHEⅡscore reduced,as well as the level of BUN and Cr.But there was no significant difference of BUN and Cr in two groups.Furthermore,the levels of TNF-α and IL-6 also declined.The efficacy in the combination treatment group was better than the CBP group(P0.05).Conclusion:The treatment of HP with CBP is effective in changing the level of inflammatory and improving patient's treatment's effect.