2014•Zhonghua zhongyiyao xuekanRequires access

Study about Curative Effect of Yiqi Huatan Sanjie Decoction Combined with Chemotherapy in Treating Advanced Colorectal Cancer

Lin Huang

Open publisher page 0 citations

Abstract

Objective: To compare the clinical curative differences between Yiqi Huatan Sanjie Decoction combined with the chemotherapy and the single chemotherapy in treating advanced colorectal cancer. Methods: 60 patients with advanced colorectal cancer were divided into two groups randomly. Patients in combined group received the treatments which included Yiqi Huatan Sanjie Decoction and the chemotherapy. The chemotherapy group only received the chemotherapy. The clinical curative effect,progressive free survival( PFS),side effects and the quality of life in the two groups were compared after 3 cycles of the chemotherapy. Result: The combined group got a higher curative rate than the chemotherapy group,but there was no significant difference between the two groups( P 0. 05). The combined group got a longer PFS,which showed a significant difference contrast with the chemotherapy group( P 0. 05). The combined group also got a lower rate of the side effects induced by the chemotherapy,such as leucopenia and vomiting,and the differences were significant( P 0. 05). Each group got an obvious improvement in the quality of life after 3 cycles of the treatment( P 0. 05),and combined group had a much better improvement than the chemotherapy group( P 0. 05). Conclusion: The combination of Yiqi Huatan Sanjie Decoction and the chemotherapy can improve the patients' PFS and the quality of life,and also can relieve the side effect of the chemotherapy than the single chemotherapy group.

About this research paper

What this paper is about

Objective: To compare the clinical curative differences between Yiqi Huatan Sanjie Decoction combined with the chemotherapy and the single chemotherapy in treating advanced colorectal cancer. Methods: 60 patients with advanced colorectal cancer were divided into two groups randomly. Patients in combined group received the treatments which included Yiqi Huatan Sanjie Decoction and the chemotherapy. The chemotherapy group only received the chemotherapy. The clinical curative effect,progressive free survival( PFS),side effects and the quality of life in the two groups were compared after 3 cycles of the chemotherapy. Result: The combined group got a higher curative rate than the chemotherapy group,but there was no significant difference between the two groups( P 0. 05). The combined group got a longer PFS,which showed a significant difference contrast with the chemotherapy group( P 0. 05). The combined group also got a lower rate of the side effects induced by the chemotherapy,such as leucopenia and vomiting,and the differences were significant( P 0. 05). Each group got an obvious improvement in the quality of life after 3 cycles of the treatment( P 0. 05),and combined group had a much better improvement than the chemotherapy group( P 0. 05). Conclusion: The combination of Yiqi Huatan Sanjie Decoction and the chemotherapy can improve the patients' PFS and the quality of life,and also can relieve the side effect of the chemotherapy than the single chemotherapy group.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective: To compare the clinical curative differences between Yiqi Huatan Sanjie Decoction combined with the chemotherapy and the single chemotherapy in treating advanced colorectal cancer. Methods: 60 patients with advanced colorectal cancer were divided into two groups randomly. Patients in combined group received the treatments which included Yiqi Huatan Sanjie Decoction and the chemotherapy. The chemotherapy group only received the chemotherapy. The clinical curative effect,progressive free survival( PFS),side effects and the quality of life in the two groups were compared after 3 cycles of the chemotherapy. Result: The combined group got a higher curative rate than the chemotherapy group,but there was no significant difference between the two groups( P 0. 05). The combined group got a longer PFS,which showed a significant difference contrast with the chemotherapy group( P 0. 05). The combined group also got a lower rate of the side effects induced by the chemotherapy,such as leucopenia and vomiting,and the differences were significant( P 0. 05). Each group got an obvious improvement in the quality of life after 3 cycles of the treatment( P 0. 05),and combined group had a much better improvement than the chemotherapy group( P 0. 05). Conclusion: The combination of Yiqi Huatan Sanjie Decoction and the chemotherapy can improve the patients' PFS and the quality of life,and also can relieve the side effect of the chemotherapy than the single chemotherapy group.

Key concepts: Medicine, Chemotherapy, Decoction, Colorectal cancer, Internal medicine, Vomiting, Gastroenterology, Quality of life (healthcare)

Related papers

Back to paper searchBrowse research topicsOriginal source
Study about Curative Effect of Yiqi Huatan Sanjie Decoction Combined with Chemotherapy in Treating Advanced Colorectal Cancer — Research Paper | ScholarLens