2004•Journal of Baotou Medical CollegeRequires access

Effects of Paeonal on Analgesia

Yang Yu-mei

Abstract

Objective:To observe the analgesic effect of Paeonal. Methods: Hot plate test and the acetic acid writhing test are used in mice. Results: Paeonal at the doses of 50.27mg/kg、25.14mg/kg and 12.57mg/kg can inhibit the writhing response induced by acetic acid and can markedly raise pain-threshold induced by heat stimulation in mice. Conclusion: Paeonal has analgesic action .

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Key concepts: Analgesic, Hot plate, Acetic acid, Stimulation, Pharmacology, Hot plate test, Chemistry, Dose dependence