Curative effect of paliperidone and risperidone on schizophrenia and its impact on social function

Objective To investigate the curative effect of paliperidone and risperidone on schizophrenia and its impact on social function.Methods 148cases with schizophrenia were were selected as the research object by sampling from Dec,2010to Dec,2013,and they were randomly divided into the control group and the experimental group,with74cases in each group.The control group were treated by risperidone,while the experimental group were treated with paliperidone.Then,the clinical effect and social function of two groups were compared.Results The efficiency rate of the experimental group was 93.24%(69/74),much higher than that of the control group which was only 78.38%(58/74),so the difference was statistically significant(P 0.01).The GQOLI-74score and PANSS score of the experimental group were better than those of the control group,and their differences between two groups had statistical significance(P0.01).Conclusion Both paliperidone and risperidone are effective in the treatment of schizophrenia,but paliperidone has better curative effect in improving the social function and quality of life of patients.Thus,it is worthy of clinical promotion.