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[Studies on chemical constituents in roots of Heracleum rapula].

Yuan-Yan Liu, Cun Zhang, Li Li, Xiao Yong-qing

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Abstract

OBJECTIVE: To study the chemical constituents in roots of Heracleum rapula. METHOD: The constituents were isolated by column chromatography on silica gel and ODS, and identified by spectroscopic methods. RESULT: Eight compounds, xanthotoxol (I), 8-geranyloxypsoralen (II), (+)-marmesin (III), beta-sitosterol (IV), stigmasterol (V), oleanolic acid (VI), ferulic (VII), scopoletin (VIII) were isolated and identified. CONCLUSION: Compounds IV, V, VI, VII, VIII were isolated from this plant for the first time.

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What this paper is about

OBJECTIVE: To study the chemical constituents in roots of Heracleum rapula. METHOD: The constituents were isolated by column chromatography on silica gel and ODS, and identified by spectroscopic methods. RESULT: Eight compounds, xanthotoxol (I), 8-geranyloxypsoralen (II), (+)-marmesin (III), beta-sitosterol (IV), stigmasterol (V), oleanolic acid (VI), ferulic (VII), scopoletin (VIII) were isolated and identified. CONCLUSION: Compounds IV, V, VI, VII, VIII were isolated from this plant for the first time.

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Available abstract

OBJECTIVE: To study the chemical constituents in roots of Heracleum rapula. METHOD: The constituents were isolated by column chromatography on silica gel and ODS, and identified by spectroscopic methods. RESULT: Eight compounds, xanthotoxol (I), 8-geranyloxypsoralen (II), (+)-marmesin (III), beta-sitosterol (IV), stigmasterol (V), oleanolic acid (VI), ferulic (VII), scopoletin (VIII) were isolated and identified. CONCLUSION: Compounds IV, V, VI, VII, VIII were isolated from this plant for the first time.

Key concepts: Scopoletin, Stigmasterol, Oleanolic acid, Chemistry, Chemical constituents, Silica gel, Chromatography, Column chromatography

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