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Effects of Tangweikang on blood glucose,serum insulin and lipids in experimental insulin resistance rats

Shaoju Jin, HU Xu-zhen

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Abstract

OBJECTIVE To study the effects of Tangweikang on blood glucose,serum insulin and lipids in experimental insulin resistance rats.METHODS The insulin resistance rats were induced by administrated high-fat and high-sugar diet.At the same time,the rats were administrated with different doses of Tangweikang.The body weight was recorded every week,blood glucose was tested every 4 weeks and 10 weeks later,and the blood glucose,serum insulin,TG,LDL-C,TC,HDL-C and liver weight were also tested,respectively.Meanwhile liver index was calculated.RESULTS Tangweikang increased the insulin sensitivity index(ISI) of insulin resistance rats ,decreased liver index and serum lipids(P0.05,P0.01),and had synergy Metformin(Met).CONCLUSION Tangweikang can improve ISI of insulin resistance rats and enhance Met effect.

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What this paper is about

OBJECTIVE To study the effects of Tangweikang on blood glucose,serum insulin and lipids in experimental insulin resistance rats.METHODS The insulin resistance rats were induced by administrated high-fat and high-sugar diet.At the same time,the rats were administrated with different doses of Tangweikang.The body weight was recorded every week,blood glucose was tested every 4 weeks and 10 weeks later,and the blood glucose,serum insulin,TG,LDL-C,TC,HDL-C and liver weight were also tested,respectively.Meanwhile liver index was calculated.RESULTS Tangweikang increased the insulin sensitivity index(ISI) of insulin resistance rats ,decreased liver index and serum lipids(P0.05,P0.01),and had synergy Metformin(Met).CONCLUSION Tangweikang can improve ISI of insulin resistance rats and enhance Met effect.

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Available abstract

OBJECTIVE To study the effects of Tangweikang on blood glucose,serum insulin and lipids in experimental insulin resistance rats.METHODS The insulin resistance rats were induced by administrated high-fat and high-sugar diet.At the same time,the rats were administrated with different doses of Tangweikang.The body weight was recorded every week,blood glucose was tested every 4 weeks and 10 weeks later,and the blood glucose,serum insulin,TG,LDL-C,TC,HDL-C and liver weight were also tested,respectively.Meanwhile liver index was calculated.RESULTS Tangweikang increased the insulin sensitivity index(ISI) of insulin resistance rats ,decreased liver index and serum lipids(P0.05,P0.01),and had synergy Metformin(Met).CONCLUSION Tangweikang can improve ISI of insulin resistance rats and enhance Met effect.

Key concepts: Insulin resistance, Internal medicine, Endocrinology, Insulin, Chemistry, Metformin, Blood sugar, Blood lipids

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Effects of Tangweikang on blood glucose,serum insulin and lipids in experimental insulin resistance rats — Research Paper | ScholarLens