Clinical Observation of Dezocine Combined with Flurbiprofen for Postoperative Analgesia after Laparoscopic Surgeries

Objective:To investigate the effects of dezocine combined with flurbiprofen for patients control intravenous analgesia(PCIA) after laparoscopic surgeries. Method:Eighty patients scheduled for selective laparoscopic surgeries were randomly divided into dezocine group(group D) and dezocine combined with flurbiprofen group(group DF), each group of 40 cases. Patients in group D were given dezocine 1.0 mg/kg+Tropisetron 5 mg+0.9% Nacl=100 mL; patients in group DF were given dezocine 0.8 mg/kg + flurbiprofen 2 mg/kg +Tropisetron 5 mg+0.9% NaCl=100 mL. Write the Visual analogue score(VAS)during both silence and 90° turn over situation,Ramsay score at 2,4,8,12,24,48 h after the operation and pressing times of PCIA and the side effect. Result: Compared with group D,patients in group DF showed no significant difference in the Ramsay score and VAS during silence,but a significant decrease in VAS under 90° turn-over was observed, and the difference between the two groups were all statistically significant(P0.05). The PCIA between the two groups were all no statistically significant. Less side effect were observed in group DF than in group DF. Conclusion: Administration of dezocine combined with flurbiprofen has a preferable therapeutic effect for post-operative movement pain and less side effect as compare to dezocine alone.